Ophthalmic formulations of cetirizine and methods of use
AssigneeAciex Therapeutics, Inc.
InventorsMark Barry Abelson, Matthew J. Chapin, Paul Gomes, George Minno, Jackie Nice
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Abstract
The present invention provides stable topical formulations of cetirizine that provide a comfortable formulation when instilled in the eye and is effective in the treatment of allergic conjunctivitis and/or allergic conjunctivitis. The invention further provides methods of treating allergic conjunctivitis and/or allergic rhinoconjunctivitis in a subject in need of such treatment by topical application of the cetirizine formulations of the invention directly to the eye.
Claims16
A topical ophthalmic formulation comprising an effective amount of cetirizine, or a pharmaceutically acceptable salt thereof, wherein cetirizine is the only active agent in the formulation and is present at a concentration of between 0.05% and 0.24% (w/v), and wherein the formulation does not contain a cyclodextrin or other solubilizing compound.
Dependencies are inferred from the claim text.