Image-guided delivery of ophthalmic therapeutics
AssigneeThe Cleveland Clinic Foundation
InventorsSunil K. Srivastava, Justis P. Ehlers, Yuankai K. Tao
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Abstract
Systems and methods are provided for image-guided delivery of therapeutics to an eye. An optical coherence tomography (OCT) imager is configured to produce at least one OCT image of the eye. A therapeutic delivery system is configured to deliver a therapeutic to the eye through a distal end of a delivery mechanism. A system control is configured to determine a position of the distal end of the delivery mechanism and control the therapeutic delivery system according to at least the determined position.
Claims20
A system for image-guided delivery of therapeutics to an eye comprising:
- an optical coherence tomography (OCT) imager configured to produce at least one OCT image of the eye;
- a therapeutic delivery system configured to deliver a therapeutic to the eye through a distal end of a delivery mechanism;
- and
- a system control configured to determine a position of the distal end of the delivery mechanism and control the therapeutic delivery system according to at least the determined position.
A method for image-guided delivery of a therapeutic to an eye comprising:
- generating at least one optical coherence tomography (OCT) image of the eye;
- determining a position of a distal end of a therapeutic delivery mechanism from the at least one OCT image of the eye;
- delivering the therapeutic to the eye through the therapeutic delivery mechanism according to the determined position of the distal end of the therapeutic delivery mechanism;
- monitoring the delivery of the therapeutic from the at least one OCT image;
- and
- controlling the therapeutic delivery system according to the at least one OCT image.
A system for automated delivery of therapeutics to an eye comprising:
- an optical coherence tomography (OCT) imager configured to produce at least one OCT image of the eye;
- a therapeutic delivery system configured to deliver a therapeutic to the eye through a distal end of a delivery mechanism;
- and
- a system control configured to monitor the delivery of the therapeutic from the at least one OCT image and control the therapeutic delivery system according to at least one of a determined flow velocity, a determined delivered volume of the therapeutic, a determined leakage of the therapeutic from the delivery site, and a determined stress on tissue at the delivery site, and a determined strain on tissue at the delivery site.
Dependencies are inferred from the claim text.