Pancreaticobiliary diversion device

Apparatus for use with pancreaticobiliary secretions that enter a gastrointestinal tract of a subject at an anatomical entry location, the apparatus comprising:

• a pancreaticobiliary secretion-diversion guide, comprising:
• first and second stent anchors coupled to proximal and distal portions of the pancreaticobiliary secretion-diversion guide respectively, and configured to apply pressure to the wall of the gastrointestinal tract in order to reduce motion of the pancreaticobiliary secretion-diversion guide within the gastrointestinal tract, the first stent anchor comprising a proximal intragastric portion and a distal pyloric portion, the proximal intragastric portion (a) having a maximum unconstrained diameter of 45-65 mm, when no forces are applied thereto, and (b) being configured to diverge in a distal to proximal direction to a maximum diverged diameter of 50-60 mm, when a squeezing force is applied to the distal pyloric portion;
• at least one resilient connecting element, each coupled to the first and second stent anchors and having a maximum diameter of 0.3-1.5 mm;
• a collection-facilitation tube between the first and second stent anchors and disposed in contact with and around the at least one resilient connecting element, the collection-facilitation tube having an inner surface and an outer surface, the inner surface defining a lumen for passage of food therethrough, the outer surface disposed to inhibit contact of the secretions with food within the lumen and configured to define a space between the outer surface and the gastrointestinal tract for collecting the secretions;
• a diversion tube, configured to:
• be in fluid communication with the space between the outer surface and the gastrointestinal tract,
• pass pancreaticobiliary secretions from the space to a location in the gastrointestinal tract that is distal to the anatomical entry location, and inhibit contact of the pancreaticobiliary secretions with food that has passed through the lumen.