Bioresorbable detachable tip design for adhesive-based extravascular closure device

A method of sealing a vessel puncture in a patient, the method comprising:

• providing a vascular closure device having a sealant delivery device, a sealing tip, and a suture connected to the sealing tip;
• advancing the vascular closure device to the vessel puncture;
• delivering a volume of flowable sealant to the vessel puncture with the sealant delivery device;
• withdrawing a portion of the vascular closure device through the volume of flowable sealant to define a channel in the volume of flowable sealant;
• releasing the sealing tip in the channel;
• extending the suture proximally from the sealing tip;
• connecting the suture to the patient.

A method of sealing a vessel puncture in a patient, the method comprising:

• providing a vascular closure device having a sealant delivery device and a sealing tip assembly, the sealant delivery device having a distal end, the sealing tip assembly being partially within the distal end and partially external to the distal end;
• positioning the vascular closure device within the vessel puncture;
• delivering a sealant material to the vessel puncture with the sealant delivery device;
• withdrawing the sealant delivery device through a channel in the sealant material;
• releasing the sealing tip assembly in the channel with a portion of the sealing tip assembly extending proximally from the sealant material;
• connecting the sealing tip assembly to the patient.

A method of sealing a vessel puncture in a patient, the method comprising:

• providing a vascular closure device having a sealant delivery device and a sealing tip assembly, the sealant delivery device having an internal cavity at a distal end of the sealant delivery device, the sealing tip assembly being at least partially within the internal cavity;
• positioning the vascular closure device within the vessel puncture;
• delivering a sealant material to the vessel puncture with the sealant delivery device;
• withdrawing the sealant delivery device through a channel in the sealant material;
• ejecting the sealing tip assembly from the internal cavity into the channel;
• connecting the sealing tip assembly to the patient.