Suture securing systems, devices and methods

A suture securing system for use in closing a vessel puncture site while eliminating the need for suture lengths to be manually tied in knots, the system comprising:

• an elongate body comprising a shaft and a barrel, the shaft having a proximal end and a distal portion, the barrel having a proximal end and a distal end comprising an opening, the barrel being mounted on the shaft such that the shaft can slide relative to the barrel, the elongate body being configured for insertion through a tissue tract to position the distal end of the barrel adjacent the vessel puncture site;
• a knot replacement element having an outer surface and an inner lumen extending therethrough, the inner lumen being configured to receive the suture lengths, the knot replacement element being at least partially positioned within the distal end of the barrel adjacent to the distal portion of the shaft and being configured to selectively fasten the suture lengths together over the vessel repair site;
• a snare having an elongate portion and a snare portion, the snare being configured to draw the suture lengths through the inner lumen of the knot replacement element and at least a portion of the elongate body;
• and
• a trimmer member configured to selectively trim the suture lengths extending proximal of the knot replacement element.