Novel immunogenic proteins of leptospira
AssigneeCornell University
InventorsYung-Fu CHANG, Raghavan U.M. PALANIAPPAN
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Abstract
The invention provides novel immunogenic proteins LigA and LigB from Leptospira for use in the development of effective vaccines and antibodies, as well as improved diagnostic methods and kits.
Claims36
1-24. (canceled)
A device comprising a solid surface, wherein at least one antibody is immobilized on the solid surface, wherein such antibody can specifically bind to a LigB protein from Leptospira interrogans, wherein the LigB protein is characterized in that it is a protein (i) comprising SEQ ID NO:
- 4, SEQ ID NO:
- 34, or SEQ ID NO:
- 46, or (ii) consisting of at least 9 contiguous amino acids of SEQ ID NO:
- 46.
(canceled)
A device comprising a solid surface, wherein at least one antibody is immobilized on the solid surface, wherein such antibody is specifically bound to a LigB protein from Leptospira interrogans, wherein the LigB protein is characterized in that it is a protein (i) comprising SEQ ID NO:
- 4, SEQ ID NO:
- 34, or SEQ ID NO:
- 46, or (ii) consisting of at least 9 contiguous amino acids of SEQ ID NO:
- 46.
Dependencies are inferred from the claim text.