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US 2016/0103126 A1Published application
Use of metal complexes
AssigneeAnteo Technologies Pty Ltd
InventorsBenjamin Ward MUIR, Michael C. BARDEN, Dennis Brian RYLATT, N. Joe MAEJI, Carmel Judith HILLYARD, Alain-Dominique Jean-Pierre GORSE, Raisa Leonidovna MONTERIO
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Abstract
A method of immobilising a target molecule on a substrate, which comprises exposing the target molecule to the substrate in the presence of a metal complex, wherein the target molecule is an unmodified target molecule, and wherein the metal complex is selected to provide a stable binding interaction between the target molecule and the substrate.
Claims7
A synthetic substrate having a surface for detection of an analyte in a sample, said surface comprising:
- a target molecule for binding to an analyte in a sample, thereby enabling detection of said analyte in said sample, wherein said target molecule has not been modified to facilitate binding with a metal ion;
- a transition metal ion having co-ordination sites bound to said target molecule and said surface, thereby binding said target molecule with said surface;
- a compound capable of forming co-ordination bonds with said transition metal ion;
- wherein said compound is an anion.
1 more element
Dependencies are inferred from the claim text.