Personalized anti-cancer agent screening system
AssigneeSamsung Life Public Welfare Foundation
InventorsDo Hyun NAM, Kyeung Min JOO
Life of this patent
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Abstract
The present invention relates to a system for screening personalized anticancer agents, a method for screening personalized anticancer agents using the system, and an apparatus for screening personalized anticancer agents. When the inventive system for screening personalized anticancer agents is used, an anticancer agent showing an optimal anticancer activity against cancer cells collected from a patient can be selected from a variety of anticancer agents, and it is possible to previously examine a therapeutic response that can appear when the selected anticancer agent is administered into the patient. Thus, the risk of trial and error in cancer therapy can be reduced, and the cost and time required for cancer therapy can be reduced.
Claims25
A method for screening personalized anticancer agents, the method comprising the steps of:
- (a) treating cancer cells from a patient with candidate anticancer agents, measuring the anticancer activity of the treated candidate anticancer agents, and selecting a group of personalized anticancer agent candidates having anticancer activity from the candidate anticancer agents;
- and
- (b) treating a xenograft animal model containing cancer cells from the patient with the selected candidate group to verify the anticancer effect of the candidate group.
A system for screening personalized anticancer agents comprise:
- (a) a means for culturing cancer cells from a patient, comprising a medium reservoir, a cell dispenser, a medium exchanger, an incubator, a stirrer and a waste discharge unit;
- and
- (b) a means for treating cultured cancer cells from the patient with the candidate anticancer agents, measuring the anticancer activity of the treated candidate anticancer agents and selecting personalize anticancer agents showing an anticancer effect, the means comprising a candidate anticancer agent reservoir, a candidate anticancer agent dispenser, a cell survival rate-measuring device, a data storage unit and a data analysis unit.
Dependencies are inferred from the claim text.