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AssigneeUniversity of Miami
InventorTan A. Ince
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Described herein are assays, methods and kits for analyzing sensitivity of a subject's cancerous tumor to a drug, predicting responses of cancerous tumors to drugs, determining the prognosis of a subject having a cancerous tumor, and developing a personalized therapy or treatment strategy for the subject. The assays, methods and kits involve analyzing gene and protein expression signatures or profiles of a subject's cancerous tumor, testing candidate drugs in cancerous cells from the subject's cancerous tumor, and classifying a subject's cancerous tumor based on ovarian cell and fallopian tube cell cell-of-origin gene expression signatures. Using these methods, a suitable drug (or drugs) is identified, the subject can be treated with that drug, and a personalized therapy can be developed for the subject.
A method for analyzing sensitivity of a subject's cancerous tumor to an oncology drug and developing a personalized therapy for the subject, the method comprising the steps of:
A method for predicting a response of a cancer patient's cancerous tumor to an oncology drug and developing a personalized therapy for the patient for treatment of the cancerous tumor, the method comprising the steps of:
A kit for analyzing sensitivity of a subject's cancerous tumor and predicting a response of a subject's cancerous tumor to an oncology drug and developing a personalized therapy for the subject, the kit comprising:
A method for determining a prognosis of a subject having an ovarian cancer tumor, the method comprising the steps of:
Dependencies are inferred from the claim text.