Pyrazolo-pyrrolidin-4-one derivatives as bet inhibitors and their use in the treatment of disease

A compound of formula (I) or a pharmaceutically acceptable salt thereof,

• wherein
• A is selected from
• B is
• C is
• R1 is methyl, optionally substituted with one or two fluoro;
• R2 is selected from chloro and fluoro;
• R3 is selected from (C1-C4)alkyl and cyclopropyl;
• and R4 is selected from (C1-C4)alkyl, optionally substituted by —OH or —O—(C1-C4)alkyl;
• halo(C1-C4)alkyl substituted by —OH;
• or
• or
• R3 is
• and R4 is selected from H;
• (C1-C4)alkyl optionally substituted by —OH or —O—(C1-C4)alkyl;
• and cyclopropyl;
• R5 is H;
• R6 is selected from methyl, methoxy, —NH2 and —NH—C(O)—(C1-C4)alkyl R7 is methoxy;
• and * indicates the point of attachment to the remainder of the molecule.