Heteroaryl compounds and methods of use thereof

A compound of formula (I):

• A-L-B (I),
• or a pharmaceutically acceptable salt or stereoisomer thereof, wherein
• L is —(C(R10)2)m—, —CR10═CR10—,
• —K—C(R10)2—, —C(R10)2—K—, or —S—;
• K is —NR11—, —O—, or —S—;
• m is 2 or 3;
• A is
• B is
• B1 is O, S, or NR8;
• B2 is CR9 or N;
• R1 is hydrogen, halo, cyano, alkyl, alkenyl, alkoxyl, aminoalkyl, heteroalkyl, cycloalkyl, aryl, heteroaryl, heterocyclyl, amino, amido, carbonyl, thiol, sulfinyl, or sulfonyl;
• each R3 is independently hydrogen, halo, cyano, alkyl, alkenyl, alkoxyl, aminoalkyl, heteroalkyl, cycloalkyl, aryl, heteroaryl, heterocyclyl, amino, amido, or thiol;
• R4 and R5 together with the atoms to which they are attached form a monocyclic or multicyclic aryl, heteroaryl, cycloalkyl, or heterocyclyl ring;
• R6 is hydrogen, halo, cyano, alkyl, alkenyl, alkoxyl, aminoalkyl, heteroalkyl, cycloalkyl, aralkyl, heteroaralkyl, aryl, heteroaryl, heterocyclyl, amino, or amido, thiol;
• R7 is hydrogen, alkyl, alkenyl, heteroalkyl, cycloalkyl, aryl, heteroaryl, or heterocyclyl;
• R8 is hydrogen, alkyl, alkenyl, heteroalkyl, cycloalkyl, aryl, heteroaryl, or heterocyclyl;
• R9 is hydrogen, halo, cyano, alkyl, alkenyl, alkoxyl, aminoalkyl, heteroalkyl, cycloalkyl, aralkyl, heteroaralkyl, aryl, heteroaryl, heterocyclyl, amino, amido, or thiol;
• each R10 is independently hydrogen, halo, or alkyl;
• and
• each R11 is hydrogen or alkyl.