Apparatus and methods for assisted breathing by transvascular nerve stimulation
AssigneeSimon Fraser University
InventorsViral THAKKAR, Joaquin Andres HOFFER, Bao Dung TRAN, Douglas G. EVANS, John Nash
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Abstract
A catheter may include electrodes for transvascular nerve stimulation. The electrodes may be positioned within lumens of the catheter and aligned with apertures in the outer wall of the catheter. The electrodes may produce focused electrical fields for stimulation of one or more nerves. In one embodiment, the catheter may include a set of proximal electrodes and a set of distal electrodes, and the proximal electrodes may stimulate a patient's left phrenic nerve and the distal electrodes may stimulate a patient's right phrenic nerve.
Claims20
A catheter, comprising:
- an elongated tubular member having a plurality of separate lumens extending along a length of the elongated tubular member, a first plurality of apertures in a side wall of the elongated tubular member, and a second plurality of apertures in the side wall of the elongated tubular member, wherein an interior of a first lumen of the plurality of lumens is connected to an exterior of the elongated tubular member by the first plurality of apertures, and wherein an interior of a second lumen of the plurality of lumens is connected to the exterior of the elongated tubular member by the second plurality of apertures;
- a first electrode assembly defining a first longitudinal axis and located within the first lumen, wherein the first electrode assembly includes a first plurality of electrodes aligned along the first longitudinal axis, and each electrode of the first plurality of electrodes is aligned with a corresponding one of the first plurality of apertures;
- and
- a second electrode assembly defining a second longitudinal axis and located within the second lumen, wherein the second electrode assembly includes a second plurality of electrodes aligned along the second longitudinal axis, and each electrode of the second plurality of electrodes is aligned with a corresponding one of the second plurality of apertures.
A catheter, comprising:
- an elongated tubular member having a plurality of lumens;
- a plurality of proximal apertures in an exterior side wall of the elongated tubular member, wherein each aperture of the plurality of proximal apertures connects an interior of one of the plurality of lumens to an exterior of the elongated tubular member, the plurality of proximal apertures includes a first row of proximal apertures and a second row of proximal apertures, and each of the first and second rows of proximal apertures extends parallel to a longitudinal axis of the elongated tubular member;
- a plurality of distal apertures in the exterior side wall of the elongated tubular member, wherein each aperture of the plurality of distal apertures is positioned distal to each aperture of the plurality of proximal apertures, each aperture of the plurality of distal apertures connects an interior of one of the plurality of lumens to the exterior of the elongated tubular member, the plurality of distal apertures includes a first row of distal apertures and a second row of distal apertures, and each of the first and second rows of distal apertures extends parallel to the longitudinal axis of the elongated tubular member;
- and
- a plurality of electrodes, wherein each electrode is positioned in one of the plurality of lumens and is aligned with a corresponding aperture of the plurality of proximal apertures or the plurality of distal apertures;
- wherein the first row of proximal apertures is positioned at a radial position different than a radial position of each of:
- the second row of proximal apertures, the first row of distal apertures, and the second row of distal apertures;
- and
- wherein the second row of proximal apertures is positioned at a radial position different than a radial position of each of:
- the first row of distal apertures and the second row of distal apertures.
A catheter, comprising:
- an elongated tubular member having a plurality of separate lumens and apertures in an exterior side wall of the elongated tubular member, wherein each aperture connects an interior of one of the plurality of separate lumens to an exterior of the elongated tubular member;
- and
- a plurality of electrode assemblies, each positioned in a corresponding separate lumen having apertures, wherein each electrode assembly includes:
- a plurality of elongated conductive members;
- and
- a plurality of electrodes aligned along a same axis, each of the plurality of electrodes being coupled to a corresponding one of the plurality of elongated conductive members by a non-conductive covering,
- wherein each of the plurality of electrodes is positioned in alignment with a corresponding aperture of the corresponding separate lumen.
Dependencies are inferred from the claim text.