Catheter Locking Solution Having Antimicrobial and Anticoagulation Properties
AssigneeBecton, Dickson and Company
InventorsJohn J. Kelley, III, Thelma I. Valdes
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Abstract
The present invention includes a catheter locking solution having both antimicrobial and anticoagulant properties including a local anesthetic and a viscosifying agent. The local anesthetic of the present invention may be an amino amide; an amino ester; an aminoacylanilide; an aminoalkyl benzoate; an amino carbonate; an N-phenylamidine compound; an N-aminoalkyl amid; an aminoketone, or combinations and mixtures thereof. In a particular embodiment of the present invention, the local anesthetic is tetracaine or dibucaine.
Claims24
A catheter locking solution comprising:
- a local anesthetic comprising at least one of dibucaine and tetracaine having anticoagulant and antimicrobial activity to reduce microbial growth and coagulation in an implanted catheter;
- and
- a viscosifying agent.
A pre-filled syringe comprising a syringe containing a locking solution, said locking solution comprising:
- a local anesthetic comprising at least one of dibucaine and tetracaine having anticoagulant and antimicrobial activity to reduce microbial growth and coagulation in an implanted catheter;
- and
- a viscosifying agent.
A catheter comprising a tube defining a lumen therethrough, wherein at least a portion of the lumen is infused with a catheter locking solution, said catheter locking solution comprising:
- a local anesthetic comprising at least one of dibucaine and tetracaine having anticoagulant and antimicrobial activity to reduce microbial growth and coagulation in the catheter;
- and
- a viscosifying agent.
Dependencies are inferred from the claim text.