Methods and processes for application of drug delivery polymeric coatings
AssigneeAriste Medical, LLC
InventorsLisa K. Jennings, Jonathan D. McCanless, Xiaoping Chen, Michael Cole
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Abstract
Polymeric coatings, their applications, and the methods of their preparation are described. The coatings may be used to confer desirable properties to the consumer and/or medical products. Also described are methods of loading therapeutic agents on the polymeric coatings and the applications of the drug eluting polymeric coatings thus obtained.
Claims30
A method of coating a product surface, the method comprising:
- (a) exposing a product surface to a coating formulation;
- (b) physically assisting the coating formulation to enter a microstructure of the product surface by applying an external force;
- and
- (c) inducing polymerization of the coating formulation to obtain the coated product surface.
The method of 4, wherein the therapeutic agent is selected from rifampicin, minocycline, minocycline hydrochloride, minocycline hyclate, or a combination thereof.
A method of preparing a coated polymeric surface, the method comprising:
- (a) providing the polymeric surface;
- (b) exposing the polymeric surface to a coating formulation;
- and
- (c) polymerizing the coating formulation on the polymeric surface to obtain the coated polymeric surface,
- wherein the coating formulation comprises a thiol monomer and an unsaturated monomer and wherein the unsaturated monomer is the same or different from the thiol monomer.
The method of 21, wherein the therapeutic agent comprises antibiotics.
The method of 21, wherein the therapeutic agent is selected from rifampicin, minocycline, minocycline hydrochloride, minocycline hyclate, or a combination thereof.
Dependencies are inferred from the claim text.