Anti-viral therapeutic for infection of the eye
AssigneeAnsun Biopharma, Inc.
InventorRonald D. Moss
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Abstract
The present disclosure provides novel compositions and methods for treating an infection of the eye resulting from an infection of a member of the Picornavirdae virus family. In particular, the present disclosure provides compounds having an anchoring domain that anchors the compound to the surface of a target cell, and a sialidase domain that can act extracellularly to inhibit infection of a target cell by a pathogen, such as a virus. The present disclosure also comprises therapeutic compositions having sialidase activity, including protein based compounds having sialidase catalytic domains. Compounds of the disclosure can be used for treating pathogenic infection to the eye.
Claims21
1-23. (canceled)
A method of treating an infection of the eye by a Picornavirdae virus, the method comprising administering to an eye of the patient a therapeutically effective amount of a compound having sialidase activity.
The method of 29 wherein the compound comprises a fusion protein wherein the fusion protein comprises at least a first portion comprising a portion of a sialidase having sialidase activity and the second portion has a net positive charge at physiological pH.
Dependencies are inferred from the claim text.