Method for the production of a medicament containing tadalafil
Assigneeratiopharm GmbH
InventorsRainer Alles, Julia Schulze Nahrup, Katrin Rimkus
Life of this patent
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Abstract
The invention relates to a method for producing a medicament containing tadalafil. In said method, tadalafil is mixed with suitable adjuvants and is heated to a temperature of about 100° C. to about 200° C., preferably about 150° C. to about 200° C., especially about 200° C.
Claims17
1-11. (canceled)
A pharmaceutical containing a solid or semi-solid solution of tadalafil, characterized in that it can be produced by a method for the production of a pharmaceutical containing tadalafil, characterized in that tadalafil is mixed with one or more suitable excipients and is heated to a temperature from approx. 100° C. to approx. 200° C., preferably from approx. 150° C. to approx. 200° C., and in particular approx. 200° C.
A pharmaceutical containing a solid or semi-solid solution of tadalafil, characterized in that 80% of the tadalafil is released in vitro after 8-120 minutes, preferably after 20 minutes.
The pharmaceutical as claimed in claim 21, characterized in that it can be produced by a method for the production of a pharmaceutical containing tadalafil, characterized in that tadalafil is mixed with one or more suitable excipients and is heated to a temperature from approx. 100° C. to approx. 200° C., preferably from approx. 150° C. to approx. 200° C., and in particular approx. 200° C.
Dependencies are inferred from the claim text.