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US 2016/0101101 A1Published application
Sublingual apomorphine
AssigneeCynapsus Therapeutics, Inc.
InventorsAnthony John GIOVINAZZO, David Bruce HEDDEN, Marc L. DE SOMER, Nathan John BRYSON
Life of this patent
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Abstract
The invention features sublingual formulations of apomorphine and apomorphine prodrugs, and methods of treating Parkinson's disease, sexual dysfunction, and depressive disorders therewith.
Claims17
-2. (canceled)
A method of treating Parkinson's disease in a subject in need thereof, the method comprising:
- (i) providing a pharmaceutical composition in unit dosage form that is a film having a first portion comprising apomorphine particles comprising an acid addition salt of apomorphine and a second portion comprising a pH neutralizing agent, wherein the film comprises the acid addition salt of apomorphine in an amount effective to treat Parkinson's disease;
- and
- (ii) administering the film by placing the film sublingually in the mouth of the subject and contacting sublingual mucosal tissue with the film.
Dependencies are inferred from the claim text.