Composition including rapamycin as active ingredient for preventing or treating hearing loss
AssigneeAjou University Industry-Academic Cooperation Foundation
InventorsYun-Hoon Choung, Yeon Ju Kim
Life of this patent
Estimating the term…
Abstract
A pharmaceutical or health food includes rapamycin as an active ingredient, the pharmaceutical or health food being applied for prevention, improvement, and treatment of ototoxic hearing loss caused by an aminoglycoside-based antibiotic, sudden sensorineural hearing loss, and noise induced hearing loss. The pharmaceutical or health food is also applied to a pharmaceutical composite preparation of an aminoglycoside-based antibiotic and rapamycin, the pharmaceutical composite preparation reducing a side effect of the aminoglycoside-based antibiotic.
Claims5
A method of preventing or treating hearing loss in a subject in need thereof, comprising:
- providing a pharmaceutical composition comprising a therapeutically effective amount of rapamycin as an active ingredient;
- and
- administering the pharmaceutical composition to the subject, wherein the hearing loss is treated,
- wherein the hearing loss is selected from the group consisting of ototoxic hearing loss caused by an aminoglycoside-based antibiotic, sudden sensorineural hearing loss, and noise induced hearing loss.
A method of preventing or treating hearing loss in a subject in need thereof, comprising:
- providing a health food comprising rapamycin as an active ingredient;
- and
- administering the health food to the subject, wherein the hearing loss is treated,
- wherein the hearing loss is selected from the group consisting of ototoxic hearing loss caused by an aminoglycoside-based antibiotic, sudden sensorineural hearing loss, and noise induced hearing loss.
A method of reducing a side effect of an aminoglycoside-based antibiotic in a subject in need thereof, comprising:
- providing a pharmaceutical composition comprising a therapeutically effective amount of the aminoglycoside-based antibiotic and rapamycin;
- and
- administering the pharmaceutical composition to the subject, wherein the side effect of the aminoglycoside-based antibiotic is reduced.
Dependencies are inferred from the claim text.