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US 2016/0097784 A1Published application
Detection of polymyxins
AssigneeRandox Laboratories Limited
InventorsElouard Benchikh, Ivan McConnell, Philip Lowry, Peter Fitzgerald
Life of this patent
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Abstract
The present invention relates to antibodies for use in detecting polymyxins and tracers; and to a single-capture immunodetection method and kits, each utilising the antibodies of the invention, and disclosed tracers.
Claims17
A hapten, immongen, or tracer having the general formula of Structure I:
- wherein;
- for the hapten, R is selected from the group consisting of benzyl and isobutyl;
- X1, X2, and X3 are each independently selected from the group consisting of a hydrogen atom (H) and SH—Z—, in which Z is a substituted or unsubstituted, straight or branched alkyl group, optionally a substituted or unsubstituted, straight or branched alkyl group of 1-10 carbon atoms;
- for the immunogen, R is selected from the group consisting of benzyl and isobutyl;
- X1, X2, and X3 are each independently selected from the group consisting of a hydrogen atom (H) and [accm-spacer-], wherein accm is an antigenicity conferring carrier material;
- and
- for the tracer, R is selected from the group consisting of benzyl and isobutyl;
- X1, X2, and X3 are each independently selected from the group consisting of a hydrogen atom (H) and [HRP-spacer-], wherein HRP is horseradish peroxidase.
5 more elements
Dependencies are inferred from the claim text.