Blood-cell producing bio-microreactor

Abstract

The present disclosure provides devices composed of a three-dimensional biocompatible matrix having hematopoietic stem or other progenitor cells embedded in the matrix, and a perfusable microvessel forming a lumen disposed within the matrix. The devices are useful for production of blood and cells and particles and for in vitro assays. The present disclosure also provides methods for generating blood cells.

Dependencies are inferred from the claim text.