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US 2016/0097031 A1Published application
Compositions of Active WNT Protein
AssigneeThe Board of Trustees of the Leland Stanford Junior University
InventorsROELAND NUSSE, KARL H. WILLERT
Life of this patent
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Abstract
Compositions of purified biologically active Wnt proteins are provided. Wnt proteins are found to be hydrophobic and post-translationally modified by addition of a lipid moiety at a conserved cysteine residue. Methods for isolation of Wnt utilize detergents that maintain the solubility of the modified protein.
Claims7
1-12. (canceled)
A method of tissue regeneration comprising contacting a cell with a dosage form comprising a Wnt protein comprising a lipid moiety.
Dependencies are inferred from the claim text.