Process for the preparation of an object supporting a lipid bilayer
AssigneeUniversiteit Twente
InventorsJasper VAN WEERD, Hermanus Bernardus Johannes KARPERIEN, Pascal JONKHEIJM
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Abstract
A process for the preparation of an object, supporting a lipid bilayer, for use in tissue engineering including the steps of providing an object having a surface, treating the surface of the object with a plasma containing active oxygen to provide the surface of the object with reactive groups A, to provide the surface of the object with reactive groups A, covalently attaching a sterol group to the reactive groups A and contacting the object activated with sterol groups with a lipid solution to form a lipid bilayer.
Claims17
A process for the preparation of an object, supporting a lipid bilayer, comprising the steps of:
- providing an object having a surface,
- treating the surface of the object with a plasma containing active oxygen to provide the surface of the object with reactive groups A,
- covalently attaching a sterol group to the reactive groups A and
- contacting the object activated with sterol groups with a lipid solution to form a lipid bilayer.
An object supporting a lipid bilayer, comprising:
- an object comprising a polymeric material,
- sterol groups covalently attached via a spacer to the polymeric material,
- a lipid bilayer surrounding the sterol groups that are covalently attached to the polymeric material and
- peptides comprising at least one hydrophobic tail attached to the lipid bilayer.
(canceled)
Dependencies are inferred from the claim text.