Microfluidic structure
AssigneeLandegren Gene Technology AB
InventorsJonas Sven Peter Jarvius, Jonas Melin
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Abstract
A microfluidic structure comprising a thermoplastic portion (200) defining a microfluidic recess (220), a bonding layer (240) on the thermoplastic portion and a siloxane elastomer portion (252) covalently bonded to the bonding layer to seal the microfluidic recess. The microfluidic recess can therefore be formed simply, quickly and cheaply using known injection moulding techniques, which are not hampered by the need for a curing step. However the positive qualities associated with elastomers can be brought to the structure by using this to seal the microchannels. The bonding layer can be formed by silica deposited on the thermoplastic portion using techniques known in the field of optics.
Claims15
A microfluidic structure comprising a thermoplastic portion defining a microfluidic recess, a bonding layer on the thermoplastic portion and a siloxane elastomer portion covalently bonded to the bonding layer to seal the microfluidic recess.
A method of manufacturing a microfluidic structure comprising the step of providing a thermoplastic portion having a microfluidic recess;
- depositing a layer of silica on the thermoplastic portion;
- oxidising the silica layer;
- and
- bringing the oxidised layer of silica into contact with an oxidised portion of PDMS to create an covalent bond.
Dependencies are inferred from the claim text.