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US 2016/0095961 A1Published application
Crosslinked coatings delivered by a balloon
AssigneeAbbott Cardiovascular Systems Inc.
InventorsJohn J. Stankus, Mikael Trollsas, Syed Hossainy
Life of this patent
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Abstract
The present invention relates to systems for and corresponding methods of delivering a therapeutic agent to a vessel wall of a body lumen by providing a compound capable of being crosslinked after intraluminal release onto a vessel wall so that the therapeutic agent is temporarily retained at the site of delivery by the crosslinked compound.
Claims8
A system to deliver a therapeutic agent to a vessel wall of a body lumen, comprising:
- (a) an expandable member having a distal end, a proximal end and a working length therebetween;
- (b) a crosslinkable compound disposed along at least a portion of the working length for intraluminal release therefrom after expansion of the expandable member, the crosslinkable compound capable of being crosslinked by solvation after intraluminal release on to a vessel wall;
- and
- (c) at least one therapeutic agent disposed along the portion of the working length so as to be temporarily retained by the crosslinkable compound after intraluminal release to the vessel wall.
1 more element
A method of delivering a therapeutic agent to a vessel wall of a body lumen, comprising:
- providing a system including (a) an expandable member having a distal end, a proximal end and a working length therebetween, (b) a crosslinkable compound disposed along at least a portion of the working length of the expandable member, and (c) at least one therapeutic agent disposed along the portion of the working length so as to be temporarily retained by the crosslinkable compound after intraluminal release to the vessel wall;
- positioning the expandable member in a body lumen;
- expanding the expandable member to contact the vessel wall for intraluminal release of the crosslinkable compound on to the vessel wall;
- and
- crosslinking the crosslinkable compound by solvation on the vessel wall with the at least one therapeutic agent temporarily retained by the crosslinked compound for delivery to the vessel wall.
2 more elements
Dependencies are inferred from the claim text.