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US 2016/0095960 A1Published application
Coating Formulations for Scoring or Cutting Balloon Catheters
AssigneeAngioScore, Inc.
InventorsUlrich Speck, Madeleine Caroline Berg
Life of this patent
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Abstract
The present invention is related to scoring or cutting balloon catheters carrying at least on a portion of their surface at least one drug or drug preparation and at least one lipophilic antioxidant at a ratio of 3-100% by weight of the at least one lipophilic antioxidant in relation to 100% by weight of the drug, wherein a combination of the at least one drug being a limus drug and the at least one lipophilic antioxidant being butylated hydroxytoluene is excluded.
Claims21
1-12. (canceled)
A balloon catheter for angioplasty or coronary angioplasty comprising:
- a shaft having a proximal portion and a distal portion;
- an inflatable balloon coupled to the distal portion of the shaft;
- a nonimplantable scoring structure surrounding the balloon, wherein the scoring structure is capable of scoring a luminal surface of a blood vessel upon inflation of the inflatable balloon;
- wherein the balloon catheter carries on at least on a portion of its surface a coating composition comprising at least one drug and at least one lipophilic antioxidant that will protect the drug from premature loss during delivery to the angioplasty site and that is 3-100% by weight of the at least one drug,
- wherein the at least one drug is selected from the group consisting of a Limus drug, a cell proliferation inhibitor, and an inhibitor of neovascularization,
- wherein the at least one lipophilic antioxidant is selected from the group consisting of butylated hydroxytoluene, butylated hydroxyanisole, nordihydroguaiaretic acid, ascorbyl palmitate, and propyl gallate, and
- wherein a combination of a Limus drug with butylated hydroxytoluene as the lipophilic antioxidant is excluded.
4 more elements
Dependencies are inferred from the claim text.