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US 2016/0095937 A1Published application
Interfering rna delivery system and uses thereof
AssigneeArrowhead Research Corporation
InventorJon E. Chatterton
Life of this patent
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Abstract
The invention provides a delivery system comprising a cell penetrating peptide, a polyarginine peptide, and an interfering RNA molecule. The system can be used for delivering interfering RNA molecules into a cell in vivo or in vitro. Therapeutic uses for the delivery system are also provided.
Claims20
An interfering RNA delivery system comprising an interfering RNA molecule linked to a cell penetrating peptide (CPP)-Arg peptide.
A method of delivering an interfering RNA molecule into a cell, comprising:
- (a) attaching an interfering RNA molecule to a CPP-Arg peptide, thereby forming an interfering RNA delivery system;
- and
- (b) administering the interfering RNA delivery system to the cell under conditions suitable for the system to enter the cell.
Dependencies are inferred from the claim text.