Promotion of wound healing
AssigneeNorthwestern University
InventorAmy S. Paller
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Abstract
The present invention provides compositions and methods that promote wound healing in a subject with a cutaneous injury. In particular, the present invention provides systemic and/or local administration of one or more compositions that cause ganglioside depletion (e.g., glucosylceramide synthase (GCS) inhibitors) for the treatment of cutaneous wounds.
Claims14
1-20. (canceled)
A method of reducing the level of GM3 in cells comprising administering to said cells a gold nanoparticle (Au NP) conjugated with a small interfering RNA (siRNA) directed against GM3 synthase (GM3S).
A composition comprising a gold nanoparticle (Au NP) conjugated with a small interfering RNA (siRNA) directed against GM3 synthase (GM3S).
Dependencies are inferred from the claim text.