Allergen Peptide Fragments and Use Thereof for Treatment of Birch Pollen Allergies

A composition comprising a plurality of contiguous overlapping peptide fragments 30 to 73 amino acids in length which peptide fragments consist of peptides within SEQ ID NOs:

• 8 and 9 which together comprise the entire amino acid sequence of a birch pollen profilin allergen (SEQ ID NO:
• 10), wherein said fragments are capable of inducing a T cell response in patients hypersensitive to said allergen
• wherein the reactivity of said peptides to IgE antibodies of subjects who are allergic to birch pollen profilin allergen is significantly reduced or eliminated while the reactivity with the T lymphocytes from subjects who are allergic to birch pollen profilin allergen is retained.