Co-administration of intravenous ibuprofen and acetaminophen for treatment of pain
AssigneeCumberland Pharmaceuticals Inc.
InventorsLeo PAVLIV, Amy Dix ROCK
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Abstract
An effective dose of intravenous ibuprofen administered co-adminstered with intravenous acetaminophen in surgery patients is a safe and effective way to reduce both pain and the need for opioid analgesics. In preferred embodiments, the administration of intravenous ibuprofen and intravenous acetaminophen starts no later than at approximately the completion of wound closure.
Claims24
A method for reducing pain in a human patient undergoing a surgical procedure, comprising intravenously co-administering effective doses of ibuprofen and acetaminophen to the patient in an amount effective to significantly reduce post-operative pain in the patient, wherein the ibuprofen and acetaminophen are intravenously administered no later than at about the time of surgical wound closure, and thereafter co-administering therapeutically effective doses of intravenous ibuprofen and acetaminophen about every 4 to about every 6 hours post-surgery for at least about 8 doses.
A method of treating surgical pain in a human patient, comprising administering about 800 mg ibuprofen intravenously at about the start of surgery, and administering about 1000 mg acetaminophen intravenously no later than at the completion of surgical wound closure.
Dependencies are inferred from the claim text.