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US 2016/0095821 A1Published application
Abuse-resistant mucoadhesive devices for delivery of buprenorphine
AssigneeBioDelivery Sciences International, Inc.
InventorsAndrew Finn, Niraj Vasisht
Life of this patent
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Abstract
The present invention provides abuse deterrent mucoadhesive devices for delivery of buprenorphine. Each device comprises a mucoadhesive layer and a backing layer, and the pH in each layer is selected, such that absorption of buprenorphine is maximized.
Claims8
An abuse deterrent mucoadhesive device for use in managing pain or opioid dependence, the device comprising:
- a mucoadhesive layer comprising an effective amount of buprenorphine buffered to a pH of between about 4.0 and about 6.0;
- and
- a backing layer buffered to a pH between about 4.0 and about 4.8.
Dependencies are inferred from the claim text.