Margin extension device and method
AssigneeCity of Hope
InventorsGagandeep Singh, Jonathan Kessler
Life of this patent
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Abstract
A margin extension device and method are disclosed herein. The margin extension device can be used for ablating one or several cancer cells and can include a contact member and a plurality of electrodes. The contact member can be electrically conductive, and can electrically connect the electrodes. The margin extension device can further include one or several leads that connect the electrodes of the margin extension device to a treatment controller. The treatment controller can include a pulse generator that can generate one or several electrical pulses that generate one or several electrical fields in tissue proximate to the margin extension device.
Claims33
A surgical margin extender comprising:
- an anode;
- a cathode;
- and
- a contact member, wherein the contact member comprises a conductive material, wherein the contact member electrically connects the anode and the cathode;
- and wherein the contact member electrically connects the anode and cathode at a distance such that the anode and the cathode can electroporate a cancer cell.
A treatment system comprising:
- a control module, wherein the control module is configured to generate at least one electrical pulse configured to electroporate a cancer cell;
- a surgical margin extender comprising:
- an anode;
- a cathode;
- and
- a contact member electrically connecting the anode and cathode in a configuration such that the anode and the cathode can electroporate the cancer cell via the transmission of the at least one pulse to a living tissue;
- and
- leads connecting the anode and the cathode to the control module.
A method of generating a negative margin around an excised tumor, the method comprising:
- excising a tumor from a living tissue, wherein the excision of the tumor does not create a negative margin at a portion of the tissue surrounding the tumor;
- applying a surgical margin extender to the portion of the tissue surrounding the tumor that does not have a negative margin, wherein the margin extender comprises:
- an anode;
- a cathode;
- and
- a contact member, wherein the contact member comprises a conductive material that electrically connects the anode and the cathode;
- and wherein the contact member electrically connects the anode and cathode at a distance such that the anode and the cathode can electroporate a cancer cell;
- and
- applying an electrical current to the contact member via the anode and cathode, wherein the application of the electrical current to the contact member via the anode and the cathode electroporates the cancer cell in the portion of the tissue to which the margin extender is applied.
A method of treating a cancer, the method comprising:
- identifying the location for providing a treatment;
- applying a surgical margin extender to tissue at the treatment location, wherein the margin extender comprises:
- an anode;
- a cathode;
- and
- a contact member, wherein the contact member comprises a conductive material that electrically connects the anode and the cathode;
- and wherein the contact member electrically connects the anode and cathode at a distance such that the anode and the cathode can electroporate the cancer cell;
- applying an electrical current to the contact member via the anode and cathode, wherein the application of the electrical current to the contact member via the anode and the cathode electroporates a cancer cell at the treatment location.
Dependencies are inferred from the claim text.