Magnetic and/or hook and loop t-tags

A method for treating a tissue opening, comprising:

• inserting a delivery device including first and second closing devices into a first portion of target tissue;
• deploying a first anchoring element of the first closing device out of the delivery device into the first portion of target tissue while retaining within the delivery device a first coupling portion of the first closing device, the first coupling portion being coupled to the first anchoring element via a first tether;
• withdrawing the delivery device from the first portion of target tissue;
• deploying the first coupling portion of the first closing device outside the first portion of target tissue;
• inserting the delivery device into a second portion of target tissue separated from the first portion of target tissue;
• deploying a second anchoring element of the second closing device out of the delivery device into the second portion of target tissue while retaining within the delivery device a second coupling portion of the second closing device, the second coupling portion being coupled to the second anchoring element via a second tether;
• withdrawing the delivery device from the second portion of target tissue;
• deploying the second coupling portion of the second closing device outside the second portion of target tissue;
• and
• coupling the first and second coupling portions to one another to draw the draw the first and second portions of target tissue toward one another and to maintain the first and second portions of target tissue in desired positions relative to one another.