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US 2016/0095580 A1Published application
Lung ventilation measurements using ultrasound
AssigneeThe Regents of the University of Michigan
InventorsJonathan Rubin, James Hamilton, J. Brian Fowlkes, Oliver D. Kripfgans
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Abstract
An ultrasound-based system determines dynamic strain measurements over a surface using ultrasound speckle analysis that allows for accurate measurement of surface area displacement. The system additionally determines an approximate displacement along a third axis, the z-axis. From these, an estimation of a local volume change is determined. In this way, a volume change can be determined for the lung or any other region of interest.
Claims11
An apparatus comprising:
- an imaging processing machine having a processor and a memory, wherein the processor is configured to execute instructions that when executed cause the imaging processing machine:
- to receive ultrasound images of a two-dimensional area corresponding to the target sample, where a first ultrasound image is taken at a first time period and a second ultrasound image is taken at a second time period after the first time period;
- to determine a change in strain value of the target sample over the two-dimensional area, wherein the strain value is determined from comparing the first ultrasound image to the second ultrasound image;
- to determine from the change in strain value, an xy-plane change in area of the target sample between the first time period and the second time period;
- to determine an approximate physical z-axis displacement over the two-dimensional area by approximating a change in local curvature of the two-dimensional area between the first time period and the second time period;
- and
- to determine a volume displacement of the target sample from the approximate physical z-axis displacement and the change in strain value.
4 more elements
Dependencies are inferred from the claim text.