Method for measuring intracranial elasticity
AssigneeArthur RAPPAPORT
InventorVitor Daniel DE VITERBO
Life of this patent
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Abstract
A novel method to noninvasively measure intracranial pressure (ICP) and more generally brain elasticity is disclosed. ICP is determined using an algorithm coupled on a simulated artificial neural network (SANN) that calculates ICP based on a determination of a set of interacted ultrasound signals (IUSs) generated from multiple ultrasound pulses. The methods and systems of the present invention are capable of rapidly determining ICP without manual review of EPG waves by a technician.
Claims12
A method of measuring elasticity of a tissue within a mammalian body, comprising the steps of:
- a. transmitting at least one ultrasound pulse into the body at a target to obtain a reflected signal;
- b. graphing the reflected signal (“s”) intensity over time (“t”) to generate an echopulsograph (“EPG”);
- c. identifying the points of variation of said signal over time;
- d. graphing said points at time (“t”) for each EPG;
- and
- e. calculating the elasticity of a tissue using a computer algorithm.
11-16. (canceled)
A method of measuring intracranial pressure (“ICP”) of a mammalian subject comprising the steps of:
- a. transmitting at least one ultrasound pulse at a target within a cranium of said subject;
- b. detecting reflected signal(s) from the transmitted ultrasound pulse;
- c. employing the reflected signal(s) to calculate the ICP, wherein
- ICP=Σ tan h(Σ/×W+b)W+b
- wherein l is an input matrix of data points based on the reflected signal(s), W is a calibration weight matrix, and b is an assigned random bias constant.
Dependencies are inferred from the claim text.