Systems and methods for ex-vivo organ care
AssigneeTransmedics, Inc.
InventorsWaleed H. HASSANEIN, Richard BRINGHAM, Giovanni CECERE, Tamer I. KHAYAL, Ronald TAYLOR, Hossam ALGAMIL
Life of this patent
Estimating the term…
Abstract
The invention provides, in various embodiments, systems, devices and methods relating to ex-vivo organ care. In certain embodiments, the invention relates to maintaining an organ ex-vivo at near-physiologic conditions.
Claims15
1-23. (canceled)
An organ chamber assembly for containing an organ for preservation, the chamber assembly comprising,
- a housing having a bottom and walls for containing the organ,
- a lid for covering the housing to substantially enclose the organ,
- a pad sized and shaped for being positioned in a bottom portion of the housing for supporting the organ, and
- at least one electrode located on the pad and placed to be in contact with the organ.
An organ chamber assembly for containing an organ for preservation, the chamber assembly comprising,
- a housing having a bottom and walls for containing the organ,
- a lid for covering the housing to substantially enclose the organ, and
- electrodes located in a bottom portion of the housing and positioned for contact with the organ.
(canceled)
An organ care system comprising:
- an organ chamber assembly for containing an organ for preservation, the chamber assembly comprising,
- a housing having a bottom and walls for containing the organ,
- a lid for covering the housing to substantially enclose the organ,
- a pad sized and shaped for being positioned in a bottom portion of the housing for supporting the organ, and
- at least one electrode located on the pad and placed to be in contact with the organ;
- and
- a pump for circulating a perfusion solution to the organ to preserve the organ.
An care preservation system comprising:
- an organ chamber assembly for containing an organ for preservation, the chamber assembly comprising,
- a housing having a bottom and walls for containing the organ,
- a lid for covering the housing to substantially enclose the organ, and
- electrodes located in a bottom portion of-the housing and positioned for contact with the organ;
- and
- a pump for circulating a perfusion solution to the organ to preserve the organ.
An organ care system comprising:
- an organ chamber assembly for containing an organ for preservation, the chamber assembly comprising,
- a housing having a bottom and walls for containing the organ,
- a lid for covering the housing to substantially enclose the organ, and
- electrodes located in a bottom portion of the housing and positioned for contact with the organ;
- a pump for circulating a perfusion solution to the organ to preserve the organ;
- and
- a heater for heating the perfusion solution.
A method of preserving an organ ex vivo, comprising
- placing a heart in an organ chamber assembly, said organ chamber assembly comprising
- a housing having a bottom and walls for containing the organ,
- an intermediate lid for covering an opening to the housing for substantially enclosing the organ within the housing, the intermediate lid including a frame, a flexible membrane suspended within the frame, the flexible membrane containing sufficient membrane material to manipulate or examine the organ, and
- an outer lid independently operable from the intermediate lid for covering, at least partially, the intermediate lid, and
- placing the organ chamber assembly in an organ care system.
Dependencies are inferred from the claim text.