Peptide domain required for interaction between the envelope of a virus pertaining to the herv-w interference group and an hasct receptor
AssigneeBiomerieux
InventorsFrancois MALLET, Guy ORIOL, Valerie CHEYNET
Life of this patent
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Abstract
A peptide domain necessary for an interaction between an envelope of a virus belonging to an HERV-W interference group and an hASCT receptor comprises (i) an N-terminus motif having an amino acid sequence selected from the group consisting of: SEQ ID No. 1 to SEQ ID No. 29, (ii) a C-terminus motif having an amino acid sequence selected from the group consisting of: SEQ ID No. 30 to SEQ ID No. 40, and (iii) at least one motif between the N-terminus and the C-terminus, and having an amino acid sequence selected from the group consisting of: SEQ ID No. 41, SEQ ID No. 42 and SEQ ID No. 73.
Claims22
A peptide domain necessary for an interaction between an envelope of a virus belonging to an HERV-W interference group and an hASCT receptor, the peptide domain comprising:
- an N-terminus motif having an amino acid sequence selected from the group consisting of:
- SEQ ID No. 1 to SEQ ID No. 29,
- a C-terminus motif having an amino acid sequence selected from the group consisting of:
- SEQ ID No. 30 to SEQ ID No. 40, and
- at least one motif between the N-terminus and the C-terminus, and having an amino acid sequence selected from the group consisting of:
- SEQ ID No. 41, SEQ ID No. 42 and SEQ ID No. 73.
A method of inhibiting an interaction between an envelope of a virus belonging to an HERV-W interference group and an hASCT receptor, the method comprising contacting an antibody with said envelope, the antibody being directed against a peptide domain comprising:
- an N-terminus motif having an amino acid sequence selected from the group consisting of:
- SEQ ID No. 1 to SEQ ID No. 29,
- a C-terminus motif having an amino acid sequence selected from the group consisting of:
- SEQ ID No. 30 to SEQ ID No. 40, and
- at least one motif between the N-terminus and the C-terminus, and having an amino acid sequence selected from the group consisting of:
- SEQ ID No. 41, SEQ ID No. 42 and SEQ ID No. 73.
Dependencies are inferred from the claim text.