Systems and methods for hyperspectral imaging

A method of diagnosing a medical condition in a subject, the subject having a plurality of regions, the method comprising:

• (a) resolving light obtained from each region of the plurality of regions into a corresponding spectrum thereby obtaining a plurality of spectrums, each spectrum in the plurality of spectrums corresponding to a region in the plurality of regions;
• (b) obtaining, using a computer, based on a stored spectral signature corresponding to the medical condition, a probability that a first spectrum in the plurality of spectrums includes indicia of the medical condition being present in the region that corresponding to the first spectrum;
• and
• (c) displaying to a user or outputting to a tangible computer readable media an indicator representing the probable presence of the medical condition in the corresponding region when the probability exceeds a pre-defined threshold.

A method of diagnosing a medical condition of a subject using a contact probe module, the subject having a plurality of regions of skin of interest, the method comprising:

• (A) resolving light obtained from each region of skin in a plurality of regions of skin of the subject into a corresponding spectrum using a hyperspectral module, thereby constructing a plurality of spectra;
• (B) identifying, using a compute, a suspect region of skin in said plurality of regions of skin by obtaining a first indication that a first spectrum in said plurality of spectra that corresponds to the suspect region includes an indicia of said medical condition being present in the suspect region;
• (C) collecting, after said identifying (B), a measurement of said suspect region using said contact probe module thereby obtaining a second indication that said medical condition is present in the suspect region, wherein said contact probe module is configured to obtain a signal from said suspect region;
• and
• (D) outputting an indicator representing the presence of the medical condition in the suspect region to a user, a user interface device, or a monitor;
• or outputting an indicator representing the presence of the medical condition in the suspect region in user readable form to a computer readable storage medium or a local or remote computer system;
• or displaying an indicator representing the presence of the medical condition in the suspect region.