Back to results
US 2016/0077084 A1Published application
Amphibian oocyte or embryo bioassay
AssigneeBoard of Trustees of the University of Arkansas
InventorsAngus MacNicol, Narsimha Reddy Penthala, Peter Crooks, Venumadhav Janganati
Life of this patent
Estimating the term…
Abstract
The present invention provides in vivo methods for screening compounds of interest. The methods rely on readily-observable phenotypic changes in amphibian oocytes or early embryos.
Claims21
An in vivo method for screening a plurality of compounds, the method comprising:
- a) contacting a plurality of amphibian oocytes or embryos with the plurality of compounds;
- and
- b) monitoring a phenotype in the plurality of amphibian oocytes or embryos to identify a compound that affects the phenotype.
A method for identifying a compound that affects a regulated mRNA translation control process, the method comprises:
- a) contacting a plurality of amphibian oocytes or embryos with a plurality of compounds;
- and
- b) monitoring a phenotype in the plurality of amphibian oocytes or embryos to identify the compound that affects the regulated mRNA translation control process.
(canceled)
Dependencies are inferred from the claim text.