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AssigneeChangwon National University Industry Academy Cooperation Corps
InventorsDongwan KIM, Han N. PARK, Gyu B. KIM
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The present invention relates to an anti-inflammatory, skin-regenerative, whitening, antioxidant, or wound-healing composition containing a culture medium of adipose-derived stem cell-T (ADSC-T) cells as an active ingredient, in which T-antigen is introduced into an adipose-derived stem cell. The culture medium of ADSC-T cells, according to the present invention, has remarkable effects for treating or inhibiting inflammation by alleviating atopic dermatitis, which is an autoimmune disease, and inhibiting NF-κB activities through an increase of an Iκbα expression. Additionally, the culture medium, according to the present invention, exhibits: excellent skin regenerative effects by having effects of enhancing skin collagen elasticity and reducing wounds, in a collagen culture; excellent skin whitening effects by inhibiting tyrosinase activities and melanin production; and excellent anti-oxidation effects by inhibiting DPPH radical activities. Furthermore, the present invention has remarkable wound-healing effects by enhancing cell mobility of fibroblast, and is thus useful for anti-inflammation, skin-regeneration, whitening, anti-oxidation, or healing wounds.
A pharmaceutical composition for preventing or treating inflammatory diseases, comprising a culture medium of adipose-derived stem cell-T (ADSC-T) cells in which T-antigen is introduced into an adipose-derived stem cell as an active ingredient.
A food composition for preventing or improving inflammatory diseases, comprising a culture medium of ADSC-T cells in which T-antigen is introduced into an adipose-derived stem cell as an active ingredient.
A cosmetic composition for improving skin-regeneration, comprising a culture medium of ADSC-T cells in which T-antigen is introduced into an adipose-derived stem cell as an active ingredient.
A food composition for improving skin-regeneration, comprising a culture medium of ADSC-T cells in which T-antigen is introduced into an adipose-derived stem cell as an active ingredient.
A whitening cosmetic composition, comprising a culture medium of ADSC-T cells in which T-antigen is introduced into an adipose-derived stem cell as an active ingredient.
A whitening food composition, comprising a culture medium of ADSC-T cells in which T-antigen is introduced into an adipose-derived stem cell as an active ingredient.
An anti-oxidation or anti-aging cosmetic composition, comprising a culture medium of ADSC-T cells in which T-antigen is introduced into an adipose-derived stem cell as an active ingredient.
An anti-oxidation or anti-aging food composition, comprising a culture medium of ADSC-T cells in which T-antigen is introduced into an adipose-derived stem cell as an active ingredient.
A pharmaceutical composition for wound-healing, comprising a culture medium of ADSC-T cells in which T-antigen is introduced into an adipose-derived stem cell as an active ingredient.
Dependencies are inferred from the claim text.