Asrgl1 in endometrial cancer
AssigneeAtlas Antibodies AB
InventorsPer-Henrik Edqvist, Fredrik Ponten
Life of this patent
Estimating the term…
Abstract
There is provided a method for determining whether a mammalian subject having an endometrial cancer belongs to a first or a second group, wherein the prognosis of subjects of the first group is better than the prognosis of subjects of the second group, comprising the steps of: a) evaluating an amount of ASRGL1 in at least part of a sample earlier obtained from the subject and determining a sample value corresponding to the evaluated amount; b) comparing said sample value with a predetermined reference value; and if said sample value is higher than said reference value, c1) concluding that the subject belongs to the first group; and if said sample value is lower than or equal to said reference value, c2) concluding that the subject belongs to the second group.
Claims25
1-25. (canceled)
A method of treatment of a subject having an endometrial cancer, comprising the steps of:
- a) evaluating an amount of ASRGL1 in at least part of a sample earlier obtained from the subject and determining a sample value corresponding to the evaluated amount;
- b) comparing said sample value with a predetermined reference value;
- and
- if said sample value is lower than or equal to said reference value,
- c) treating said subject with an endometrial cancer treatment regimen.
A method for determining whether a mammalian subject having an endometrial cancer belongs to a first or a second group, wherein the prognosis of subjects of the first group is better than the prognosis of subjects of the second group, comprising the steps of:
- a) evaluating an amount of ASRGL1 in at least part of a sample earlier obtained from the subject and determining a sample value corresponding to the evaluated amount;
- b) comparing said sample value with a predetermined reference value;
- and
- if said sample value is higher than said reference value,
- c1) concluding that the subject belongs to the first group;
- and
- if said sample value is lower than or equal to said reference value,
- c2) concluding that the subject belongs to the second group.
A method for determining whether a first or a second number of lymph nodes shall be removed from a mammalian subject having an endometrial cancer, wherein the first number is higher than the second number, comprising the steps of:
- a) evaluating an amount of ASRGL1 in at least part of a sample earlier obtained from the subject and determining a sample value corresponding to the evaluated amount;
- b) comparing said sample value with a predetermined reference value;
- and
- if said sample value is higher than said reference value,
- c1) removing the second number of lymph nodes;
- and
- if said sample value is lower than or equal to said reference value,
- c2) removing the first number of lymph nodes.
An affinity ligand capable of selective interaction with an ASRGL1 peptide consisting of 25 amino acid residues or less and comprising a sequence selected from SEQ ID NO:
- 11, 13, 14 and 15.
Dependencies are inferred from the claim text.