Suppression of cancer metastasis
AssigneeAcademia Sinica
InventorsShu-Mei Liang, Ching-Feng Chiu, Shao-Wen Hung, Jei-Ming Peng, Chi-Ming Liang
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Abstract
Methods of using fibrillar proteins are provided for suppressing cancer metastasis. Cancer metastasis is the most common cause of treatment failure and death in cancer patients. Tumor cell invasion and/or migration can be significantly inhibited after fibrillar proteins (rVP1, F-HSA, and F-BSA) treatment in vitro. In addition, rVP1 can significantly suppress murine and human breast cancer metastasis and human prostate and ovarian cancer metastasis in vivo while F-HSA can significantly suppress murine breast cancer metastasis.
Claims16
A method for suppressing cancer metastasis comprising:
- administering to a subject an effective amount of fibrillar proteins and a pharmaceutically acceptable carrier, wherein said administering reduces cancer metastasis in said subject.
Dependencies are inferred from the claim text.