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US 2016/0033474 A1Published application
Alpha-keto-isovalerate as a biomarker of prebiotic efficacy for weight gain prevention
AssigneeNestec S.A.
InventorsFrancois-Pierre Martin, Sebastiano Collino, Ivan Montoliu Roura
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Abstract
The present invention relates generally to the field of nutrition and health, particular, the present invention relates to alpha-keto-isovalerate as a biomarker urine of the efficacy of prebiotics for the prevention of diet induced weight gain.
Claims20
A method for predicting and/or quantifying the response of a subject to prebiotics in the prevention of diet induced weight gain, comprising
- a) determining a level of alpha-keto-isovalerate in a urine sample obtained from a subject that has consumed prebiotics, and
- b) comparing the subject's alpha-keto-isovalerate level to a predetermined reference value,
- wherein a decreased alpha-keto-isovalerate level, or an absence of change in the alpha-keto-isovalerate level, in the urine sample compared to the predetermined reference value indicates that the administration of prebiotics is effective in the prevention of diet induced weight gain in the subject.
A biomarker in urine for predicting and/or quantifying the response of subjects to prebiotics in the prevention of diet induced weight gain, wherein the biomarker is alpha-keto-isovalerate.
(canceled)
Dependencies are inferred from the claim text.