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US 2016/0033473 A1Published application
Indoxyl sulfate as a biomarker of prebiotic efficacy for weight gain prevention
AssigneeNestec S.A.
InventorsFrancois-Pierre Martin, Sebastiano Collino, Ivan Montoliu Roura
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Abstract
The present invention relates generally to the field of nutrition and health. In particular, the present invention relates to indoxyl sulfate as a biomarker in urine of the efficacy of prebiotics for the prevention of diet induced weight gain.
Claims20
A method for predicting and/or quantifying the response of a subject to prebiotics in the prevention of diet induced weight gain, comprising
- a) determining a level of indoxyl sulfate in a urine sample obtained from a subject that has consumed prebiotics, and
- b) comparing the subject's indoxyl sulfate level to a predetermined reference value,
- wherein a decreased indoxyl sulfate level, or an absence of change in the indoxyl sulfate level, in the urine sample compared to the predetermined reference value indicates that the administration of prebiotics is effective in the prevention of diet induced weight gain in the subject.
A biomarker in urine for predicting and/or quantifying the response of subjects to prebiotics in the prevention of diet induced weight gain, wherein the biomarker is indoxyl sulfate.
(canceled)
Dependencies are inferred from the claim text.