Novel pi polyamide
AssigneeNihon University
InventorsDaisuke OBINATA, Satoru TAKAHASHI, Kyoko FUJIWARA, Satoshi INOUE, Kenichi TAKAYAMA
Life of this patent
Estimating the term…
Abstract
To provide a safe and stable medicine useful for prevention and treatment of prostate cancer. A novel PI polyamide is acquired that recognizes and binds to a specific base sequence of an Oct1 gene binding sequence present in a transcriptional regulatory region (AR response region) of an ACSL3 gene and regulating the transcription activity of AR. This leads to the provision of an ACSL3 gene expression inhibitor and a preventive and/or therapeutic agent of prostate cancer containing the PI polyamide as an active ingredient.
Claims4
(canceled)
A pyrrole-imidazole polyamide binding to the whole or a part of a base sequence indicated by SEQ ID NO:1, the pyrrole-imidazole polyamide being represented by any of following Formulas 1 to 3.
Dependencies are inferred from the claim text.