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AssigneeMangoGen Pharma, Inc.
InventorsSatya PRAKASH, Arghya PAUL, Dominique SHUM-TIM
Estimating the term…
The present disclosure provides viral microparticles comprising genetically-engineered baculoviruses (at least partially) embedded in a polymeric matrix for the local delivery of therapeutic nucleic acid molecules to the cells of a vertebrate individual (optionally in combination with a medical implant such as vascular stent platform). The viral microparticles are especially useful for promoting the healing of a wound as well as the repair of a blood vessel and prevent pathological scarring. Also provided herein are processes for making the viral microparticles, pharmaceutical compositions comprising viral microparticles as well as supports comprising the viral microparticles for the locating the viral microparticles in a wound or in the vicinity of a wound.
A viral microparticle for the delivery of a recombinant therapeutic nucleic acid molecule to the cells of a vertebrate individual, said viral microparticle comprising:
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12-14. (canceled)
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A process for making a viral microparticle for the delivery of a recombinant therapeutic nucleic acid molecule to the cells of a vertebrate individual, said process comprising:
20-21. (canceled)
25-26. (canceled)
A process for formulating the pharmaceutical composition of claim 25, said process:
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A kit for making the pharmaceutical composition of claim 25, said kit comprising:
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33-36. (canceled)
Dependencies are inferred from the claim text.