Genetically modified microorganism for producing long-chain dicarboxylic acid and method of using thereof
AssigneeIndustrial Technology Research Institute
InventorsHsin-Ju Hsieh, Liang-Jung Chien, Jia-Hung Wang, Yu-Ju Lin
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Abstract
Described herein are genetically-modified microorganisms for producing long-chain dicarboxylic acids and methods of using the microorganisms. The microorganisms contain a first nucleic acid encoding an Umbellularia californica lauroyl ACP-thioesterase (BTE) operably linked to a promoter or a second nucleic acid encoding a Cocos nucifera lauroyl ACP-thioesterase (FatB3) operably linked to a promoter.
Claims20
A genetically modified microorganism, comprising a first nucleic acid encoding an Umbellularia californica lauroyl ACP-thioesterase (BTE) operably linked to a promoter or a second nucleic acid encoding a Cocos nucifera lauroyl ACP-thioesterase (FatB3) operably linked to a promoter, wherein the microorganism produces an increased amount of long-chain dicarboxylic acids as compared to the unmodified parent of the microorganism.
Dependencies are inferred from the claim text.