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US 2016/0009733 A1Published application
Regulation of nitric oxide release and biofilm development
AssigneesNewSouth Innovations Pty Limited, University of Wollongong
InventorsNicolas Barraud, Bharat Gangadhar Kardak, Michael John Kelso, Staffan Kjelleberg, Scott Rice
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Abstract
The present invention relates generally to methods and compounds for regulating the release of nitric oxide in the vicinity of biofilm-forming microorganisms to regulate programmed cell death in the microorganisms and thereby promote dispersal of microorganism from biofilms and/or inhibit biofilm formation or development. More particularly, the invention relates to the use of compounds to provide spatial and temporal control over nitric oxide release.
Claims54
A compound of the formula (I), or a salt thereof:
- wherein T is a bond or a linker, R2 and R3 are organic residues and X is selected from the group consisting of:
- wherein R1 is an organic residue.
Dependencies are inferred from the claim text.