Tricyclic lactam derivatives as 11-beta hydroxysteroid dehydrogenase inhibitors

A compound of formula

• the N-oxide forms, the pharmaceutically acceptable addition salts and the stereochemically isomeric forms thereof, wherein
• X represents C;
• Y represents N;
• L represents a methyl or a direct bond;
• Z1 represents a direct bond, C1-2alkyl- or a divalent radical of formula —CH2—CH═ (a) or —CH═ (b);
• Z2 represents a direct bond, C1-2alkyl- or a divalent radical of formula —CH2—CH═ (a) or —CH═ (b);
• R1 represents hydrogen, halo, cyano, amino, phenyl, hydroxy, C1-4alkyloxycarbonyl, —O—(C═O)—C1-4alkyl, hydroxycarbonyl, NR3R4 or C1-4alkyl wherein said C1-4alkyl or —O—(C═O)—C1-4alkyl are optionally substituted with one or more substituents selected from halo, hydroxycarbonyl, phenyl, C1-4alkyloxy or NR5R6 or
• R1 represents C1-4alkyloxy- optionally substituted with one or more substituents selected from halo, hydroxycarbonyl, phenyl, C1-4alkyloxy or NR7R8;
• R2 represents hydrogen, halo, C1-4alkyl or C1-4alkyloxy-;
• R3 and R4 each independently represent hydrogen, C1-4alkyl or C1-4alkylcarbonyl-;
• R5 and R6 each independently represent hydrogen, C1-4alkyl or C1-4alkylcarbonyl-;
• R7 and R8 each independently represent hydrogen, C1-4alkyl or C1-4alkylcarbonyl-;
• A represents phenyl or a monocyclic heterocycle selected from the group consisting of thiophenyl, furanyl, oxazolyl, thiazolyl, imidazolyl, isoxazolyl, isothiazolyl, pyrridinyl, pyridazinyl, pyrimidinyl and piperazinyl.