Diagnostic tools to predict onset of preeclampsia
OwnerJustin L. GROBE, Mark K. SANTILLANinventors
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Abstract
Assays, kits, methods, and devices for diagnosing or predicting the likelihood of occurrence preeclampsia in a subject are disclosed.
Claims20
A kit for diagnosing or predicting the likelihood of occurrence of preeclampsia in a subject, comprising an antibody detection assay specific for the detection of copeptin in a sample taken from the subject, wherein the sample is taken during the first trimester of pregnancy.
A method of diagnosing or predicting the likelihood of occurrence of preeclampsia in a subject, the method comprising:
- collecting a urine sample from a subject during the first trimester of pregnancy;
- and
- measuring differences in copeptin levels compared to a control using an antibody detection assay.
A kit for diagnosing or predicting the likelihood of occurrence of preeclampsia in a subject, comprising an enzyme detection assay specific for the detection of LNPEP in a sample taken from the subject.
A test device for predicting whether a subject is predisposed to developing preeclampsia, comprising:
- a substrate comprising a test assay for detection of a protein product of the vasopressin gene;
- a sample application area;
- and
- a read out area;
- wherein upon application of a sample from a subject by a user, the test device provides information to the user indicating whether the subject is pregnant and whether the subject is predisposed to developing preeclampsia.
Dependencies are inferred from the claim text.