Antioxidant compositions for soft oral tissue and methods of formulation and use thereof
AssigneePerio Sciences, LLC
InventorsJan Zielinski, Thomas Russell Moon, Edward P. Allen
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AssigneePerio Sciences, LLC
InventorsJan Zielinski, Thomas Russell Moon, Edward P. Allen
Estimating the term…
One embodiment of the invention is directed to an oral antioxidant composition including between 0.0001% and 5.0% w/w antioxidant, wherein the antioxidant includes cinnamic acid derivative, tetrahydrocurcuminoids, or phloretin and an orally pharmaceutically acceptable carrier. The composition may have a pH of at least 5.0. According to still further embodiments, the composition may also include between 0.0001% and 5.0% w/w of one or two more additional antioxidants that include cinnamic acid derivative, tetrahydrcurcuminoids, phloretin, or a stilbene derivative. In more particular embodiments, the cinnamic acid derivative may include trans-ferulic acid, the tetrahydrocurcuminoids may include tetrahydrcurcuminoids CG™, or the stilbene derivative may include resveratrol. Other embodiments may relate to methods of treating or preventing an oral disease by applying topically an antioxidant composition as described above.
1-48. (canceled)
A method of treating gingivitis or periodontitis, or both comprising applying topically to a soft oral tissue an oral antioxidant composition in an amount and for a time sufficient to increase migration of a gingival cell or periodontal cell, or both in the soft oral tissue, thereby treating the gingivitis or periodontitis, or both, the antioxidant composition comprising:
51-58. (canceled)
Dependencies are inferred from the claim text.